If you have cancer, call your doctor if any of the following occur:
- You have new pain.
- Your drugs or other treatments are no longer working.
- Your pain medicine is not working long enough after each dose.
- You have new symptoms, such as having a hard time walking, eating, or urinating.
- You have side effects, such as nausea or vomiting, constipation, or diarrhea.
- Your pain makes it hard for you to do your daily activities, such as eating or sleeping.